By
Sampson I.M Onwuka
There are chances that the
bi-product of the human bodies which are physical and which separate us from
each other, can be traced to the last returning few months. How the body carry
viruses and bacteria that the body pushing out.
In practice, the total amount of
virus and disease that can exit the body or at least circulate within a given
community may be considered relatively comparable to the amount of human
activity in this period, it may remain within the comparative ration until
unusual activity such as industrial expansion or disease bearing animals not
familiar with an environment and ecosystem interferes, then there is event
horizon.
From the levels of the DNA
philosophy and the ordering knowledge of the Sciences available to us today,
there is no question that it is a mistake to view without reason or even
without books, that a certain virus could possibly exist somewhere in the
Universe that do not have the basic DNA familiar to mammals, that do not have a
basic structure that can be understood and tampered it, and can be used in
experimental isolation of several key minerals in the body or in the body of
the animals which they came from.
For instance, a Histone and
Histamines are minerals based Enzymes that can be extracted from Birds and Calf
as well. Histones are found in the Calf Thymus and in Spleen and Liver of
bovine mammals, but in all, they can also be found in the Spermatozoa of these
Bovine creatures.
Between the Thymus of Calf and its Spermatozoa is one product
that are found the in the mucosa intestine, will not propelled a connection
between Thymus and Spermatozoa, ready-make the answer the secret of mammalian
existence in the final product or Spermatozoa. We seem common that a different
exist between the HIV and HLTV viruses given the structure of their heads in
the aspects of the protein that enucleate these viruses. The helical difference
between these two viruses and the part of the wine…
That the human body, by some means
manages to regulate itself through signals towards the release of enzymes,
which from the Age of his writing and even now, leans towards digestive system.
The connection of poor performance of the Pancreatic juice is not unrelated to
Insulin, which he created to have argued as responsible for ‘diabetes mellitus’
or cancer of the insulin.
A measure of his theories about the
body and its regulating ability is in the of Science known to more concerned to
the role of Chromosome 5, the Chromosome that enables that body to regulate
itself through the adaptive mechanism of the nasal which connects to the ear
membranes where the major sources of Cold Air for instance are usually passed
from the external to the internal.
The explicit role of the ‘Histamine
and the Tubermo Nucleus’ (Myron Scholes) in managing the brain (hypothalamus)
reaction to temperature towards the release of enzymes in the body, has been
extended to the areas of Alzheimer and Schizophrenia, with view that the
changes that take in human brain may be due to internal factors other diseases
which was initially argued as hereditary.
The aspect of histamine and the
association of histamine to fever and influenza (flu) now elaborates on the
works of Bernard but clarifies the role of the RNA proteins in exchange of
information between the brain the current temperature of human body, that it is
entirely possible to catch cold from freezing largely due to the body’s ability
to relay as much information through the hypothalamus towards a defense system
which can be altered even without foreign elements.
We may suggest that the chain of
discretion between Robert Gallo and Luc Montaigner survives differently, that
for instance it survives in similar work of some of the latter day scientist,
especially in HIV emphasis and Zaire strain of Chimpanzee.
Following the footsteps of Robert Gallo
and perhaps an effective scientist on his own right is Jaap Goudsmit, who like
Frederick Sanger, developed major interest in the biology in ways that were not
exactly placed on perspective, particularly in HIV studies where he is
considered one of the foremost authority on HIV, Beatrice Hahn, Myron Scholes,
Michael Gothlieb, Michael Popovic, Jay Levy being among the notable names, of
course Myron Essex of Harvard School of Medicine and Myron Scholes of North
Carolina could be added, but these are primary list, associated with specific
invective and are schools on their own including David Baltimore.
In Guadsmit (1997) we try our faith
on the virus in the context of the life-strain which has been in the possession
of Gallo, for all intent of academic reasons, there is a mention that a
familiar kind of strain used in navigating the earliest promises of the
viruses, and his book, ‘Nature of AIDSD’ is a 1976 “isolate of (strain HZ321)
is our earliest actual of HIV, since no virus has yet been recovered from the
Norway sailor” and this isolate was comparable to the Zairian HIV – IA isolate
and seem to be comparable to HTLV – I and Human T-cell lymphoma and Leukemia
viruses,* and “Also known as lymphotropic viruses, these retroviruses are not
lentiviruses but oncoviruses. They seldom cause disease or meet HIV in the same
cell but are prospective HIV partners for production of recombinants. In
monkeys they are STLV – I and II.”
But according to Deusberg (2003),
in 1985; Gallo changed the name in 1985….for the human T-cell leukemia virus –
substituted it for human T-cell lymphotropic virus meaning infecting T-cells,
that “A sample of the leukemic T-cells, originally named HUT78, was sent to his
lab for isolating leukemia virus.” But Deusberg did not specify the strain of
virus that Gallo took, whether it was the one from Zaire or some district in
Africa.
That they dovetail the leukemia
causing cancer virus in Cancer, means to add that their prognosis of the Feline
oncogenic virus – (virus cancer primary concerned with Cats and particularly
through breathing) is prove that the Elly Lilly and Rockefeller Institute were familiar with the ‘…cases of
‘Feline AIDS” (FAIDS), which are Deusberg mention was isolated as “simian
immunodeficiency virus” and blamed it for “AIDS” in monkeys (SAIDS), all of
which are product of the 40’s in U.S and in France, and then 50’s were the
curtain gradually fell for the rest of the biological scientist.
There other foundations of Biology
and medicine that are important, used in part by Peter Deusberg in his
arguments against Gallo and Montagnier that viruses capable of causing epidemic
should be new viruses – set in order of Koch – where the theory was also placed
in different in terms of (Farr) on the veracity of a New Virus capable of
creating epidemic.
In short summary HIV could did not
meet the criteria for a new virus since it was always in the system and in fact
no new epidemic could arrive human being through new and direct process since
all life from a nearest beginning is part of some evolutionary pathway and
therefore not new, that new cold cases which arrive either by day or by night
in human to human environment, were not new viral cases deserving of a new
category such as a case of HIV or immune deficiency virus, which Peter Deusberg
argued was not a new cold virus and does not need doctors to defend it, that it
was simply not previously diagnosed.
This situation of great importance
given the issue of detecting a new virus and its pathology, for if we agree
with Deusberg, Koch, Farr, that there are viruses out there that has not made
contact with us, that these viruses are not new viruses and therefore not
different from the cold, we may consider disabusing our emphasis on detection
and mainly detection whose purpose is well served to the evolutionary path or
pathology of the very virus.
What Deusberg argues for can mainly
be understood from other elements of immune deficiency syndrome, that the cold
cases of drug induced autoimmune deficiency were as rampart as the drug and
cocktail induced 60’s as they were in 80’s. We betray some of the perceived
argument from Deusberg by stating that there elements of disagreement in his
book set against Luc Montaigner, that attempt to place emphasis on the
redoubtable origins of the Virus – HIV – suffer a consequence given the more
mature arguments which could have emerged from his book.
One of the perceived argument is
role of evolutionary pathway of the Virus – that given the lack new definition
and misdiagnosis of HIV or any virus, there are other reasons why it could have
surfaced in specific periods on human existence – for instance during high
period of human activity, air pollution, and zoonotic episodes on man and the
primates.
In addition to these periods are
cases of human activity, that drugs can weaken human immune system, for
instance Cortison as demonstrated by many experts and in very recent case by
Abraham Verghese, where the introduction of Cortison shots to the body of Rat
can give the rat some induced metabolic process especially in case of the rat’s
activity that the Cortison shot end up damaging the immune system of the Rat
leading to specific cold spells detrimental from blood.
Dr O.U Orji in Nigeria have also
found the use of Cortison to have undiluted effects on human blood, the cause
of this is not exactly well known, but we can be sure, that the blood structure
– especially Hemeglobin is affected by the presence of certain chemicals – such
as Cortison (steroids) – which the body need since it widen the protein gates
of the body and induces rapid chemical and enzymic reaction leading to
increased body activity and blood flow but it ends, altering the structure of
sugar complex and nucleotide phosphates for instance Thymus, which is the
weakest link in the DNA bases plate.
Apparently all connection necessary
for generating new life and possibly creating one adapts to the thymus, which
is the very important in production of CD4 and human immune system – and
cortison – no less steroid or in many ways than one, testosterone builds as
well weak the human elective immune system – especially the male. Taken differently, drugs and drug induced
energy products including for instance Gensing is considered a blood thinner
for reasons of its reserved ability to delay the oxidation process and the role
of sugar necessary to stay oxygen in the blood since the body because of valium
do not retain oxygen for long hence we are tired for reasons of life.
Blood damage can occur naturally
and like cancer can occur due to genes borrowed from parents, but in terms of
artificial breakdown of the human blood and the defense mechanism, it is
prolong exposure of the body to damages of all types that induce poor repair
strategy for thymus leading to weak and vulnerable immune system no different
from HIV.
While we may indicate that the
whole statement raised by these experts are true, they are true to the extent
that the body could easily adjust to changes in the body and in the environment
if and when the exposure to the system does no prove fatal. It is taken that
these viruses capable of destroying the body in slow or speed motive are doing
so for many reasons including that the body and CD4 cannot keep up.
However there is no going that HIV
is an infectious disease in keeping to Deusberg and in Order of Farrs - HIV
viruses do not meet the criteria for infection, adding that the virus is
considered a retrovirus essentially to the careers of Gallo, Baltimore, and Montaigne,
whereas retrovirus and the reverse transcription of RNA to DNA and DNA to RNA
though an enzyme, means that HIV could have been the reasons for AIDS as
according to Deusberg, but in all, shows that the total damage that the body
can sustain is sufficient to satisfy its healing and its cure so long the
exposure does not directly and indirectly kill the system composed mainly of
active cells. But he is wrong about the dual undeserving dual purpose of HIV,
for it to be considered a fallacy; there is something about the changes in
human body that accompanies the changes in one’s genetic component.
I shall doubt that HIV lead to AIDS under all
circumstances, that some are by nature predisposed to autoimmune diseases and
have problem of weak immune system making vulnerable to serious and challenging
which like cases such as HIV in stages from virions suffer the victim to ends
as end becomes those with compromised immune system open to extreme cold.
In
comparative analysis on all that is well discussed and well-rehearsed about
human immune system, it is not HIV a virus and study by itself that kills the
victim, it is the weakness of the immune system resulting from weak and
depraved blood structure and oxygen – cortisone and thymus – that leads to
leads to the premature break-up of A helical structure of the blood
(Hemoglobin) which is well studied by Linus Pauling and Max Delbruik,
Salvatore, leading to the crystalized structure of human DNA and body, and the
intellectual history show how the body link the chemicals together in what they
call Chemical Bonding and the DNA dogma defined by Watson and Crick in 1953.
David Suzuki and Peter Knudtson…
studies in metabolic deficiencies such as Lesch-Nyhan me….Amniocentesis –
performed during 14th and 16th weeks of pregnancy, the presence for example,
“…the red blood cells of people born with a hereditary illness called
glucose-6-phosphate dehydrogenase (6-6-PD) deficiency – a disproportionate
number of whom happen to be members of racial or ethnic minorities – are
thought to be more susceptible to damage from oxygen depletion during prolonged
exposure to naphthalene and other industrial chemicals than are the red blood
cells of other people.”
The gene therapy for sickle-cell
anemia would involve inserting copies of the desired DNA sequence into ‘living
bone marrow cells’ in other to perform a desired function…and the basic steps
for gene therapy which is has a lot of promising career is that it helps to
welter down the sudden presence of oncogene in the blood and the blood
cells. It is through the amplified focus
of gene and blood padding, which gives the body a kind of immune defense
without necessarily resorting to the body and the cells in the system to fight
the onset of HIV and its attempt at penetrating the cells from where it begins
to immortalize.
One of the instruments applied is
the knowledge application of the knowledge that a single gene resident in Red
Blood cells (Hemoglobin) was responsible for sickle anemia. This argument was
made especially clear Linus Pauling and his group of scientists, does not
differ from the role of genes leading to the damage of an enzyme in the body,
which Joshua Lederberg made very clear.
This gene therapy therefore makes
its seem obvious that the comparative association of the gene replacement in
direct auto-immune cases such anemia and sickle cells, can be applied to HIV
since the breakdown of the body begins from the attachment of the Virus to the
human immune system.
Without the defense system that circulates the surface of
the cells, there is a possibility that the body could withstand HIV or similar
virus except that the condition which is not far from the Hemophiliac, could
essentially suffocate the virions which entered the body. Although the rapid
cells division of the Virus suggests it may be not be possible, it is however
reasonable that the earlier a victim begins a treatment the better. Gene
therapy is not sufficient enough in nestling the problem of HIV.
Heterozygous sickle cell traits
from both partners may warrant their children stand 25% chance of having
homozygous sickle cell anemia would involve inserting copies….the desired DNA.
Bone marrow cells are the source of a patient’s genetically defective red blood
cells…..“….cancerous blood-forming cells in a patient suffering from Leukemia,
for example, are replaced with cells from a healthy, tissue matched
donor….”Gene therapy for sickle-cell anemia would involve inserting copies….the
desired DNA sequences into ‘living bone marrow cells’ in other to perform a
desired function…..
The basic steps in gene Therapy for
sickle cell Anemia…..
Oncogene sudden change…
Vulnerable to untimely collapse
each time blood oxygen levels decrease….The genetic Basis of sickle-cell
Anemia, it affects the production of one genetic pool for identical normal
hemoglobin, sickle cells – and low (blood) red blood cells…
Linus Pauling – and his group
demonstrated a ‘single molecule’ defect resident in Red Blood cells hemoglobin
was responsible for sickle-cell anemia. To demonstrate this as they placed
Hemoglobin proteins in a gelatinous substance and exposing it to weak
electrical current (electrophoresis) which demonstrates the chemically based
difference between two separated. What
they also discovered is that when the valine which is an Amino acid is turned
off with glutamic acid, it directly alters the shape of the hemoglobin which is
usually three dimensional given the arrangement of the Amino Acid.
When the mutant S hemoglobin (Red
Blood cells) encounters low oxygen blood concentration, the hemoglobin becomes
erratic in a bid to form its own crystal structure and ends forming a structure
that is quite different from the three dimensional regular Amino Acid. The
result is that the structure based loosely on a fractured composition causes
the cells to collapse. In essence the sickle cell after a while is returns or
re-encounters an oxygen rich part of the cells and circulatory system, these
formative molecules break-up, which is on contact with oxygen-rich blood,
allowing the red blood to return to its regular shape…
One of the more contentious of this
period which lends itself to Enders in some level, it is the charismatic
clarity of Chemical bonding at the level of human blood and hemoglobin and how
the permeation of Sickle Cells and other blood cancers were undeserved death
sentences.
Where certain chemicals can induce the worst human reactions, that
they can damage the crystal structure of any blood leading to premature
explosion of the walls, it is well studied that the real reasons behind the
poor regulation of the oxygen in the blood or in some cases, poor regulation of
sugar in the blood resulting to a different pancreatic cancer called Diabetes,
Sickle cells enfeebles the victim by squeezing the consumption of rate and
hence the duplicity of red blood cells in the human body, whose primary role as
a b complex is to condition the profligate activity of the white blood cells
primary thymus depended.
You are no longer in control of
your senses when the red blood count decreases and panic and headache no less
different from advanced types of diabetes send the patient various ends of pain
and aneurysm and the body demands its shots. It is the lacks of red bloods and
high dose of white cells that signals the beginning of the age of new infection
in the body.
These are side effects which
medicine over the course of the last 30 years has helped to undress but the
main events of the HIV is what happen to the blood and the rest of body –
especially the spleen which a personal theory – leads away from the old into
the new and back to the old that the HIV is a virus that induce various forms
of blood cancer, that it means the body progressively vulnerable to invasion,
that we thin out due to the role of the virus and we die gradually and
grudgingly from AIDS since the body is no longer at ease with blood stimulus –
hence poor production of red blood cells……..
That in limelight of those who
discovered the oncogene viruses or isolated it from the strain of a cancer
causing virus, it was achieved in 1951 at Rockefeller Institute from possibly a
strain of the Congo virus. It means that the dives on Gallo’s HIV buffs, is
probably not new, may started as a trial in the context of the theories about Viruses and primitive
parts of Africa.
If we are to break it
down, it almost seem to point out the that strain of Gallo’s virus that was
available for processing and was available for early consumptive laboratory
work was from a strain of the virus from Zaire, that it may have a common
physiology with the strain of those of the Norwegian sailor, even in his
estimate the man was no longer available.
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